【研究分野】生体医工学・生体材料学

【研究領域課題番号】17K17682 (KAKENデータベースで見る）

【研究キーワード】

Nanopore / DNA sequencing / Bionanosensing / Diffusiophoresis / 2D materials / Joule heating / Diffusion current / Two-dimensional material / Biosensing / 2D material / Ion transport / Electrokinetics / Precision medicine / Drug delivery / ナノチューブ / マイクロ・ナノデバイス / 分析科学 / 生体分子

【研究成果の概要】

It was demonstrated that the structural information of ssDNA molecules can be revealed using artificial solid-state nanopores. The proposed isothermal sensing method by diffusion current has simultaneously resolved the excess DNA translocation speed and high thermal noise issues.

【研究の社会的意義】

This project has made a remarkable progress by increasing the nanopore sensing resolution, which paves the way for DNA sequencing using solid-state nanopores. This breakthrough not only opens up new opportunities for molecule sequencing, but provides hopes to high resolution proteomic analysis.

【研究種目】若手研究(B)

【研究期間】2017-04-01 - 2019-03-31

【配分額】3,900千円 (直接経費: 3,000千円、間接経費: 900千円)